The Proof with Simon Hill

• Does Keto Accelerate Heart Disease? What the New Study Didn’t Tell You | Simon Hill, Msc, Bsc

  In this solo episode, I unpack the controversial new KETO-CTA study and why its conclusions about cholesterol, ApoB, and ketogenic diets aren’t as clear as they seem. We break down what the study really found, how it was communicated, and what it means if you (or someone you care about) is following a high-fat, low-carb diet with elevated LDL-C. With expert commentary from Dr. Alan Flanagan, we explore: Who Lean Mass Hyper-Responders (LMHRs) are Why the study isn’t actually a “trial” The missing data on plaque progression and what was left out What non-calcified plaque volume (NCPV) tells us Whether this study really challenges ApoB’s role in heart disease Why communication matters and how headlines can mislead What this means for keto diets, cardiovascular risk, and informed decisions If you found this valuable, please share it or leave a review. Every share helps the truth cut through the noise. Intro: Can You Be “Healthy” with Sky-High LDL on Keto? (00:00) What the Keto CTA Study Was Trying to Prove (01:36) The Problem: This Wasn’t Actually a Clinical Trial (03:57) APOB Focused, But Not Pre-Registered: Red Flag #1 (07:58) Real Plaque Progression Numbers: 4x Faster Than Healthy Controls (09:16) So… Does ApoB Matter or Not? (17:50) How the Study Was Communicated to the Public (26:03) What the Headlines Should Actually Say (37:05) Final Thoughts from Dr. Carvallo and Dr. Flanagan (38:06) Key Takeaways (40:37) Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family. This episode is brought to you by: 38TERA Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code PROOF for 25% off at checkout. Bragg Bragg Organic Apple Cider Vinegar is raw, unfiltered, and naturally fermented with 100% organic apples, always with the live “Mother” in every bottle. Get 20% off your first order at bragg.com with promo code SIMON. IM8 With 92 nutrients, including Vitamin B12, Iodine, Selenium and Vitamin D, in highly absorbable forms, IM8 Daily Essentials is the perfect all-in-one daily multi-vitamin to ensure you meet your daily micronutrient needs. IM8 is offering an exclusive 10% off your first order with a free welcome kit when you enter the promo code SIMON at checkout on im8health.com LMNT Stay hydrated with LMNT. Get a free Sample Pack of LMNT’s most popular drink mix flavours with any purchase at DrinkLMNT.com/SIMON Find your favourite LMNT flavour, or share with a friend. And if you don’t like it? Full refund, no questions asked. Eight Sleep Upgrade your sleep with the Pod 5 Ultra by Eight Sleep. Clinically validated to deliver up to 1 extra hour of quality sleep per night through temperature control and biometric tracking. Use code THEPROOF for $350 off at eightsleep.com/theproof. Try it risk-free for 30 days, with worldwide shipping. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. Simon Hill, MSc, BSc (Hons) Creator of theproof.com Host of The Proof with Simon Hill Author of The Proof is in the Plants Subscribe & Connect: YouTube Apple Podcasts Spotify Instagram: @simonhill X: @theproof Facebook: The Proof with Simon Hill Nourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.

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  50:41
• Supplements, Cholesterol, Sea Moss Hype & Why I Do What I Do | Ask Me Anything #3

  In this rapid-fire solo episode, I’m answering your questions straight from the community. From creatine and multivitamins to cardiovascular risk, sea moss, weight gain, soy, grief, and more, no fluff, just focused insights backed by science. What I cover: What matters more when choosing creatine: NSF certification or Creapure Should you take creatine daily? Healthy weight gain strategies Key cardiovascular blood markers to track How to manage high Lp(a) and familial hypercholesterolemia Thoughts on sea moss, multivitamins, soy, oils, and ultra-processed foods How much protein is enough on a plant-based diet Personal updates on running, sleep, and a new iron absorption study Reflections on grief, gratitude, and future plans Want to dive deeper into any of these topics? Explore links to studies, products, and past episodes at theproof.com. Intro (00:00) Creatine: Best Type & Daily Use Explained (00:00:46) How to Gain Healthy Weight on a Plant-Based Diet (00:02:15) Essential Blood Tests for Heart Health (00:03:55) CGMs for Non-Diabetics: Helpful or Hype? (00:06:02) Saunas & Longevity: What the Science Says (00:07:02) Lp(a), ApoB & Cholesterol: What Actually Matters? (00:08:36) Can You Reduce Familial Hypercholesterolemia Risk? (00:13:05) How Low Should LDL Go? (00:16:04) Iron Absorption in Vegans vs Omnivores (00:16:41) Best Sources of Protein on a Plant-Based Diet (00:20:22) Key Nutrient Tests for Vegans (00:21:46) Multivitamins & Pescatarian Diets: Are They Worth It? (00:22:26) Supplements for Bone Health: Vitamin K2, D & More (00:27:31) Sea Moss & CoQ10: Superfoods or Marketing? (00:28:41) Is Soy Really Bad for You? (00:30:14) Are Oils Healthy? What to Know About Fats (00:31:41) Zone 2 Training: How Much Do You Need? (00:37:06) Do You Eat Ultra-Processed Vegan Food? (00:40:37) Why This Work Matters & What Drives the Mission (00:44:55) Outro (00:49:45) Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family. This episode is brought to you by: 38TERA Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for 10% off at checkout. Function Health Take charge of your health with advanced blood testing and personalised insights. Function Health provides a practical solution to track key health markers such as cholesterol, blood sugar, and more. For the first 1,000 listeners, new members get a $100 credit when signing up. Head to functionhealth.com/simonhill to claim your credit. Only available to those living in the United States. Momentous My go-to supplement brand for protein and creatine is Momentous. Get 20% off your first purchase by using the code LIVINGPROOF at checkout at livemomentous.com Pique Tea Pique's Nandaka provides sustainable, all-day energy and makes you feel like you’re doing something good for your body! Try Pique and get 20% off plus a FREE starter kit when you shop exclusively at Piquelife.com/simon. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. Simon Hill, MSc, BSc (Hons) Creator of theproof.com Host of The Proof with Simon Hill Author of The Proof is in the Plants Subscribe & Connect: YouTube Apple Podcasts Spotify Instagram: @simonhill X: @theproof Facebook: The Proof with Simon Hill Nourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.

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  52:40
• Changing Our Relationship With Pain | Dr Emily Musgrove

  What if trying to feel good all the time is actually keeping you stuck? In this episode of The Proof, I’m joined by Dr. Emily Musgrove, clinical psychologist and author of Unstuck, to explore why emotional discomfort isn’t something to avoid, but something to understand. We unpack what it really means to be “stuck,” how avoidance sneaks into everyday life (even among high performers), and the role of values, awareness, and psychological flexibility in creating meaningful change. In this episode, we cover: Why feeling stuck doesn’t mean you’re broken How emotional avoidance drives disconnection The difference between psychological flexibility and cognitive fusion The cost of always performing and staying polished Hedonic vs. eudaimonic wellbeing How to clarify values and live with intention One practical step to start moving forward If you’re feeling overwhelmed, burned out, or just unsure of what’s next, this conversation offers clarity, compassion, and tools to help you reconnect with what matters. Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family. This episode is brought to you by: 38TERA Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code PROOF for 25% off at checkout. Fireflies Stay focused and let Fireflies handle the notes. From transcriptions and summaries to real-time voice commands, Fireflies turns your meetings into actionable insights, seamlessly integrating with Zoom, Google Meet, Slack, and more. Sign up for a yearly plan and get two months FREE at fireflies.ai/theproof. Bragg Bragg Organic Apple Cider Vinegar is raw, unfiltered, and naturally fermented with 100% organic apples, always with the live “Mother” in every bottle. Get 20% off your first order at bragg.com with promo code SIMON. Shopify Shopify, the world's leading e-commerce platform, helps you turn browsers into buyers with the internet’s best-converting check out–up to 36% better compared to other leading e-commerce platforms. To boost your conversion rate, and grow your business, sign up for a one-dollar-per-month trial period at shopify.com/proof. Eight Sleep Upgrade your sleep with the Pod 5 Ultra by Eight Sleep. Clinically validated to deliver up to 1 extra hour of quality sleep per night through temperature control and biometric tracking. Use code THEPROOF for $350 off at eightsleep.com/theproof. Try it risk-free for 30 days, with worldwide shipping. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. Simon Hill, MSc, BSc (Hons) Creator of theproof.com Host of The Proof with Simon Hill Author of The Proof is in the Plants Subscribe & Connect: YouTube Apple Podcasts Spotify Instagram: @simonhill Twitter: @theproof Facebook: The Proof with Simon Hill Nourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.

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  1:22:38
• Nutrition, Protein & Misinformation | Simon Hill on Food For Thought with Rhiannon Lambert

  This week, I’m sharing a conversation I had as a guest on Food For Thought, the podcast hosted by registered nutritionist Rhiannon Lambert. We covered everything from protein and plant-based diets to the role of ultra-processed foods in chronic disease, and how to better interpret nutrition science in a world full of misinformation. In this episode, I cover: How to think critically about nutrition research The impact of plant-based diets on human and planetary health Protein quality and building muscle with plants The role of ultra-processed foods in long-term health Social media’s influence on nutrition discourse What phytates are and whether they matter This is a repost of my chat with Rhiannon. You can find her podcast and more of her work at rhitrition.com/podcast. Intro: The Science Behind Plant-Based Nutrition and Longevity (00:00) Simon's Journey from Sports Physio to Nutrition Science Advocate (00:35) Why Nutrition Science Requires Context and Nuance (05:12) Debunking Common Nutrition Myths with Evidence (05:59) Health Benefits of Adopting a Plant-Based Diet (15:30) Protein and Muscle: Separating Myths from Data (21:42) Key Nutrients to Monitor in Plant-Based Eating (31:21) Understanding Calories: Not All Energy Is Equal (35:56) Phytates and Mineral Absorption: Myths vs. Mechanisms (43:55) Environmental Impact of Dietary Choices: Data-Driven Insights (50:22) Fact or Fiction: Science-Based Answers to Nutrition Claims (55:02) Final Thoughts: Navigating Nutrition Science with Integrity (01:00:55) Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family. This episode is brought to you by: 38TERA Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code PROOF for 25% off at checkout. Function Health Take charge of your health with advanced blood testing and personalised insights. Function Health provides a practical solution to track key health markers such as cholesterol, blood sugar, and more. For the first 1,000 listeners, new members get a $100 credit when signing up. Head to functionhealth.com/simonhill to claim your credit. Only available to those living in the United States. Momentous My go-to supplement brand for protein and creatine is Momentous. Get 20% off your first purchase by using the code LIVINGPROOF at checkout at livemomentous.com Eight Sleep Upgrade your sleep with the Pod 5 Ultra by Eight Sleep. Clinically validated to deliver up to 1 extra hour of quality sleep per night through temperature control and biometric tracking. Use code THEPROOF for $350 off at eightsleep.com/theproof. Try it risk-free for 30 days, with worldwide shipping. Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Follow this link for 20% off one-time purchases and subscriptions. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. Simon Hill, MSc, BSc (Hons) Creator of theproof.com Host of The Proof with Simon Hill Author of The Proof is in the Plants Subscribe & Connect: YouTube Apple Podcasts Spotify Instagram: @simonhill Twitter: @theproof Facebook: The Proof with Simon Hill Nourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.

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  1:10:48
• Protect Your Arteries, Protect Your Life: Dr. Laurence Sperling Explains How

  Heart disease doesn’t start when you’re older, it starts early, often without symptoms. In this episode, I speak with Dr. Laurence Sperling, one of the world’s leading experts in preventive cardiology, to explore how to catch heart disease early and stop it in its tracks. We cover cholesterol, blood pressure, calcium scores, lifestyle, and more. This is one of the most practical, empowering episodes on heart health I’ve ever recorded. What we cover: Early detection and the true origins of atherosclerosis How low your cholesterol and blood pressure should really be Understanding ApoB, Lp(a), and genetic risk When it’s worth getting a CT scan Lifestyle and medical interventions that actually work Whether you’re 25 or 65, this conversation is packed with insights that can help you live longer and better by understanding and protecting your cardiovascular system. 0:00:00 – Intro 0:01:24 - Why Prevention Should Start Before Birth 0:10:11 – Is It Genetics or Lifestyle? Understanding Risk 0:16:17 – Public Health Strategy That Prevents Millions of Heart Attacks 0:21:55 - How Geography and Income Impact Heart Disease Risk 0:29:25 – Familial Hypercholesterolemia and Lifetime Cholesterol Exposure 0:34:00 – What Diet and Lifestyle Patterns Lower Risk Long-Term 0:45:49 – LDL, HDL, and the New Science of Non-HDL Cholesterol 0:53:39 - Does High Blood Pressure Still Harm Arteries if ApoB Is Low? 1:05:24 – Lipoprotein(a): The Triple Threat You Should Know About 1:08:22 – When Should You Start Cardiac Risk Assessments? 1:17:23 - Can a Calcium Score of Zero Be Misleading in Younger Adults? 1:23:58 – CT Calcium vs. CT Angiogram: Which Scan Is Right? 1:33:25 - Is Subclinical Atherosclerosis the Same as Heart Disease? 1:40:03 - What Are Optimal LDL and Blood Pressure Levels to Prevent Heart Disease? 1:48:07 – How GLP-1 Drugs Help With Weight and Heart Disease Prevention 1:57:10 – Public Health Policies That Could Save Millions 2:01:19 – Cardiologist-Approved Daily Habits for a Healthy Heart 2:05:20 – Outro This episode is brought to you by: 38TERA Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code PROOF for 25% off at checkout. LMNT Stay hydrated with LMNT. Try their limited-time Lemonade Salt flavour - salty, tart, and super refreshing. Receive a free LMNT sample pack with any order when you purchase via drinklmnt.com/simon. And if you don’t like it? Full refund — no questions asked. Pique Tea Pique's Nandaka provides sustainable, all-day energy and makes you feel like you’re doing something good for your body! Try Pique and get 20% off plus a FREE starter kit when you shop exclusively at Piquelife.com/simon. Eight Sleep Upgrade your sleep with the Pod 5 Ultra by Eight Sleep. Clinically validated to deliver up to 1 extra hour of quality sleep per night through temperature control and biometric tracking. Use code THEPROOF for $350 off at eightsleep.com/theproof. Try it risk-free for 30 days, with worldwide shipping. Function Health Take charge of your health with advanced blood testing and personalised insights. Function Health provides a practical solution to track key health markers such as cholesterol, blood sugar, and more. For the first 1,000 listeners, new members get a $100 credit when signing up. Head to functionhealth.com/simonhill to claim your credit. Only available to those living in the United States. Simon Hill, MSc, BSc (Hons) Creator of theproof.com Host of The Proof with Simon Hill Author of The Proof is in the Plants Subscribe & Connect: YouTube Apple Podcasts Spotify Instagram: @simonhill Twitter: @theproof Facebook: The Proof with Simon Hill Nourish your gut with my Plant-Based Ferments Guide and download my Two-Week Meal Plan.

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  2:13:41

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