Forget crash diets: How to maintain a healthy weight | Alan Aragon & Prof. Sarah Berry
Most people who try to lose weight and keep it off end up failing. But what if the problem isn’t you - it’s the diet?
In this episode, we cut through the noise of weight loss fads to explore a science-backed method that’s helped countless people make real, sustainable changes. It’s called flexible dieting, and it’s built around the idea that personalised macronutrient targets, food quality, and consistency matter more than restrictive rules or trendy plans.
Our guest is Alan Aragon, a leading expert in fitness nutrition who’s spent over 30 years coaching clients and publishing research that’s reshaped how the industry thinks about fat loss. Alongside Alan is Professor Sarah Berry, ZOE’s Chief Scientist, who brings insight from her studies on metabolism and how our bodies respond to food.
Together, they unpack what actually works for long-term fat loss — and how you can get started with a realistic, effective approach that doesn’t require cutting out the foods you love.
Unwrap the truth about your food 👉 Get the ZOE app
🌱 Try our new plant based wholefood supplement - Daily 30+
*Naturally high in copper which contributes to normal energy yielding metabolism and the normal function of the immune system
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Timecodes
00:00 Forget crash diets
03:42 The REAL reason we're all gaining weight
10:50 Does the keto diet work?
13:15 High-carb or high-fat diet for weight loss
18:22 The biological reason you regain weight
19:26 What is the 'YOLO margin' and how can it help you lose weight?
22:53 How a single treat becomes a daily habit
24:22 The mindset trick to stop binge eating for good
27:53 How to turn your body into a metabolic engine
29:26 No.1 rule for PROTEIN intake
33:53 A surprising take on Ozempic
38:00 The hidden danger of weight loss drugs
39:23 Step one is NOT diet or exercise
42:02 Why poor sleep makes you crave junk food
47:50 Optimal protein for fat loss
49:07 The easiest way to hit your daily protein goal
51:17 The only 3 exercises you really need
53:58 How to do 80 squats a day without even trying
56:32 This simple eating trick can cut 15% of your calories
59:50 A final warning for anyone trying to lose weight
📚Books by our ZOE Scientists
The Food For Life Cookbook
Every Body Should Know This by Dr Federica Amati
Food For Life by Prof. Tim Spector
Free resources from ZOE
Live Healthier: Top 10 Tips From ZOE Science & Nutrition
Gut Guide - For a Healthier Microbiome in Weeks
Mentioned in today's episode
Resistance Training Combined With Diet Decreases Body Fat While Preserving Lean Mass Independent of Resting Metabolic Rate: A Randomized Trial
Effects of meal frequency on weight loss and body composition: a meta-analysis
Does Timing Matter? A Narrative Review of Intermittent Fasting Variants and Their Effects on Bodyweight and Body Composition
International society of sports nutrition position stand: diets and body composition
New insights in the mechanisms of weight-loss maintenance: Summary from a Pennington symposium
Have feedback or a topic you'd like us to cover? Let us know here.
Episode transcripts are available here.
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1:05:31
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1:05:31
Recap: How to start fermenting at home | Sandor Katz
Today, we’re diving into fermentation.
If you’re a regular ZOE listener, you’ve probably heard that fermented foods are some of the best things you can eat for your gut health. Packed with beneficial microbes, they’ve been shown to boost everything from digestion to immune function.
Still, the idea of at home fermentation - cultivating bacteria and microorganisms in your fridge - can feel a little daunting. More like a science experiment than a culinary adventure.
That’s where Sandor Katz comes in. He’s a fermentation revivalist, bestselling author, and the driving force behind a global fermentation movement. So if you're a total beginner or just sauerkraut-curious, this episode will give you the tools, the confidence, and maybe even the craving to get fermenting at home.
🥑 Unwrap the truth about your food 👉 Get the ZOE app
🌱 Try our new plant based wholefood supplement - Daily30+
*Naturally high in copper which contributes to normal energy yielding metabolism and the normal function of the immune system
📚 Books from our ZOE Scientists:The Food For Life Cookbook by Prof. Tim Spector
Food For Life by Prof. Tim Spector
Every Body Should Know This by Dr Federica Amati
Free resources from ZOE:
Live Healthier: Top 10 Tips From ZOE Science & Nutrition
Gut Guide - for a healthier microbiome in weeks
Have feedback or a topic you'd like us to cover? Let us know here
Listen to the full episode here
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10:45
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10:45
Nutrition Scientist: This is why you're confused about ultra processed food | Prof. Sarah Berry
Scientists agree that processed foods are contributing to poor health — but when it comes to ultra-processed foods (UPFs), there’s growing confusion. The term is now used so broadly that it includes everything from crisps and sweets to wholemeal bread and plant-based milks.
So what do we really know about the health effects of UPFs? And is the label actually making it harder for us to eat well?
In this episode, Jonathan is joined by Dr. Sarah Berry, ZOE’s Chief Scientist. Sarah is a professor of nutrition at King’s College London who has run some of the world’s largest human nutrition studies. Her work explores how different foods — and how they’re processed — impact metabolism, fat storage, and long-term health.
Sarah shares insights from her recent global conference talks, breaking down the good, the bad, and the misunderstood sides of ultra-processed food. By the end, you’ll have a clearer, more nuanced view of how to eat for your health — without falling for the hype.
Unwrap the truth about your food 👉 Get the ZOE app
🌱 Try our new plant based wholefood supplement - Daily 30+
*Naturally high in copper which contributes to normal energy yielding metabolism and the normal function of the immune system
Follow ZOE on Instagram.
Timecodes
00:00 Introduction
02:50 The scary headlines about your food are wrong
07:40 The food classification system scientists call 'useless'
09:25 Why not all peanut butters are created equal
11:05 What really makes a processed food unhealthy?
12:20 The difference between 'safe' and 'healthy' food additives
15:50 What food companies remove from your food
17:30 The invisible 'food matrix' that processing destroys
19:05 Why you don't absorb all the calories you eat
22:25 An apple vs apple juice: the shocking results of a 1977 study
25:05 The ingredient label lie you're falling for
26:25 Why soft food makes you gain more weight
28:40 Even a nutrition scientist with 25 years of experience is confused
32:45 How we're building a new system to score processed food
35:52 The science of 'hyper-palatable' foods
39:00 How food is engineered to make you overeat
42:10 It's not 65% of food, it's this much you should worry about
45:30 The financial reality of eating healthy
51:47 Using processing for good: the 'wonder bread' of the future
55:17 If I switch to low-risk food, will my health improve?
56:45 Is processed food damaging our brains' hunger signals?
📚Books by our ZOE Scientists
The Food For Life Cookbook
Every Body Should Know This by Dr Federica Amati
Food For Life by Prof. Tim SpectorFree resources from ZOE
Live Healthier: Top 10 Tips From ZOE Science & Nutrition
Gut Guide - For a Healthier Microbiome in Weeks
Have feedback or a topic you'd like us to cover? Let us know here.
Episode transcripts are available here.
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1:00:47
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1:00:47
Recap: Simple steps to prevent allergies | Prof. Gideon Lack
Today, we’re turning our attention to allergies.
For decades, conflicting advice on how to prevent allergies from developing has left parents unsure about the best ways to protect their children. Should you introduce peanut products to your newborn, or avoid them entirely? Many are still unclear.
What is clear, however, is that allergies are on the rise.
I’m joined by groundbreaking researcher Dr. Gideon Lack to help bring clarity to the conversation about allergies. His pioneering work has challenged long-held beliefs and offers potentially life-saving advice. He begins by sharing his first ‘lightbulb moment.’
🥑 Unwrap the truth about your food 👉 Get the ZOE app
🌱 Try our new plant based wholefood supplement - Daily30+
*Naturally high in copper which contributes to normal energy yielding metabolism and the normal function of the immune system
📚 Books from our ZOE Scientists:
The Food For Life Cookbook by Prof. Tim Spector
Food For Life by Prof. Tim Spector
Every Body Should Know This by Dr Federica Amati
Free resources from ZOE:
Live Healthier: Top 10 Tips From ZOE Science & Nutrition
Gut Guide - for a healthier microbiome in weeks
Have feedback or a topic you'd like us to cover? Let us know here
Listen to the full episode here
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14:19
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14:19
No.1 Protein Scientist: Are you eating enough? | Prof. Stuart Phillips & Dr. Federica Amati
Are you eating enough protein? This is probably a question you’ve asked yourself. With “high protein” labels on almost every type of food product you can imagine, it’s easy to get confused.
In this episode, Prof. Stuart Phillips explains how protein can keep us healthy as we age. He also outlines when we should eat protein, how much protein we really need, and provides simple, practical advice to help you achieve it. Stuart is a professor in the Kinesiology Department at McMaster University. He’s the author of more than 400 scientific papers, many focusing on protein and muscle health, particularly during ageing.
With so much confusion around this topic - especially in the context of fitness and ageing - this episode will provide clear, evidence-based answers from one of the world’s leading scientists on the topic, to help you make smarter nutrition choices.
🥑 Make smarter food choices. Become a member at zoe.com - 10% off with code PODCAST
🌱 Try our new plant based wholefood supplement - Daily 30+
*Naturally high in copper which contributes to normal energy yielding metabolism and the normal function of the immune system
Follow ZOE on Instagram.
Timecodes
00:00 We’ve been lied to about protein
04:05 Why protein is completely different from carbs and fat
09:05 The depressing age when you start losing muscle
14:45 Your muscles have a secret second job
17:25 Why food companies are suddenly adding protein to everything
22:25 The shocking protein intake that fuelled your biggest ever growth spurt
26:45 Why the 'optimal' amount of protein is so hard to define
33:05 The surprising truth about protein for building muscle
40:15 Most of us are already eating the 'optimal' amount of protein without trying
42:30 When eating more protein could actually be harmful
45:00 The ‘anabolic window’ myth debunked
48:50 Why 'animal protein is superior' is an outdated idea
51:16 The myth of ‘incomplete’ plant proteins
51:55 The ancient food secret our ancestors discovered all over the world
53:50 Is there an upper limit for protein in one meal?
57:25 My number one food for a high-protein breakfast
59:05 A simple pyramid for choosing the healthiest protein sources
59:55 The 'healthy' protein source that’s a class one carcinogen
01:02:55 When a protein bar is no healthier than a chocolate bar
01:04:30 Why your protein cookie could be reducing your healthy life years
01:06:20 My number one tip for health (and it’s not about nutrition)
01:08:50 The ideal daily protein target for most healthy adults
Studies:
Optimizing adult protein intake during catabolic health conditions, 2020, Advances in Nutrition
Integrated myofibrillar protein synthesis in recovery from resistance exercise with and without multi-ingredient supplementation in overweight older men, 2019, Frontiers in Nutrition
Higher dietary protein during weight loss: muscle sparing?, 2018, Obesity
What is the optimal amount of protein to support post-exercise skeletal muscle reconditioning in the older adult?, 2016, Sports Medicine
📚Books by our ZOE Scientists
The Food For Life Cookbook
Every Body Should Know This by Dr Federica Amati
Food For Life by Prof. Tim Spector
Free resources from ZOE
Live Healthier: Top 10 Tips From ZOE Science & Nutrition
Gut Guide - For a Healthier Microbiome in Weeks
Have feedback or a topic you'd like us to cover? Let us know here.
Episode transcripts are available here.
The world’s top scientists explain the latest health, nutrition, and gut health research and translate it into practical advice to improve your health & weight. Join ZOE Science & Nutrition, on a journey of scientific discovery. Hosted by Jonathan Wolf.
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