The Human Upgrade: Biohacking for Longevity & Performance

Scientists Test Vibrating Mattress To Help Clear Alzheimer's-Related Proteins From The Brain
Researchers at the University of Oulu in Finland tested a vibrating mattress combined with nitroglycerin, a blood-vessel-relaxing drug, in 29 healthy adults and found that blood levels of amyloid-beta 42 increased approximately 35% following the combined treatment. Published in Nature Communications, the study also identified MRI changes suggesting altered cerebrospinal fluid dynamics, potentially involving the glymphatic system and mechanosensitive Piezo1 ion channels. While the results suggest increased movement of brain-associated proteins into circulation, they do not establish that Alzheimer's plaques were removed or that cognition improved. Host Dave Asprey explores the potential of mechanical stimulation, nitric oxide signaling, and brain waste clearance as emerging approaches to neurodegenerative disease prevention, and why sleep and vascular health remain essential to protecting long-term cognitive performance.
Sources:
https://doi.org/10.1038/s41467-026-78894-y
~~~

Yale Researchers Discover Taurine Controls A Key Inflammatory Switch Linked To Aging
Yale researchers identified a previously unrecognized role for taurine in regulating the NLRP3 inflammasome, an immune signaling complex associated with chronic inflammation and biological aging. Published in Cell, the research found that activated macrophages released up to 80% of their intracellular taurine, while restoring taurine suppressed inflammatory signaling. Surprisingly, circulating taurine levels were higher in older adults than younger adults, challenging the assumption that taurine universally declines with age and highlighting the importance of intracellular nutrient regulation. Host Dave Asprey examines the connection between taurine, inflammaging, immune function, and longevity, explaining why cellular nutrient availability may matter more than blood concentrations and what this emerging mechanism means for supplementation and inflammation management.
Sources:
https://doi.org/10.1016/j.cell.2026.09.061
~~~

Blood And Plasma Donation Shown To Reduce Forever Chemicals In Human Trial
A randomized clinical trial involving 285 Australian firefighters found that regular blood and plasma donation significantly reduced circulating concentrations of certain PFAS, the persistent environmental pollutants commonly known as forever chemicals. Published in JAMA Network Open, the study found that plasma donation every six weeks reduced average PFOS concentrations by 2.9 ng/mL over 12 months, compared with a 1.1 ng/mL reduction from whole-blood donation every 12 weeks and virtually no change in the control group. Because PFAS bind to proteins in blood, removing plasma offers a direct method of reducing circulating chemical concentrations, although the trial did not establish long-term health benefits. Host Dave Asprey explains why this physical removal strategy deserves attention alongside conventional detoxification approaches, and how reducing exposure through drinking water, food packaging, and environmental sources remains a critical first step.
Sources:
https://doi.org/10.1001/jamanetworkopen.2022.6257
~~~

HHS Eases Restrictions On Six Popular Biohacking Peptides Including BPC-157 And MOTS-c
On October 28, 2026, the Department of Health and Human Services announced a draft enforcement-discretion policy covering six compounded peptides: BPC-157, Epitalon, KPV, MOTS-c, Semax, and TB-500. Under the interim approach, HHS says it does not intend to take enforcement action against qualifying compounders when specific manufacturing, sourcing, formulation, labeling, and adverse-event reporting conditions are satisfied, while the FDA's formal regulatory evaluation continues. The announcement represents a significant shift for compounds being investigated or promoted for tissue repair, inflammation, mitochondrial function, cognitive performance, and longevity, although none received FDA approval through this action. Host Dave Asprey discusses what the policy could mean for peptide access, pharmaceutical regulation, product purity, and medical oversight, and why better manufacturing standards must accompany expanded access to experimental therapies.
Sources:
https://www.federalregister.gov/d/2026-22192
https://www.hhs.gov/sites/default/files/hhs-503a-peptide-enforcement-discretion-policy-appendix-b.pdf
https://www.foley.com/insights/publications/2026/10/peptides-hhs-announces-limited-enforcement-discretion-for-compounding-of-six-peptides/
~~~

Drinking Coffee Linked To 39% Lower Recurrence Hazard Of Atrial Fibrillation In Clinical Trial
A randomized clinical trial published in JAMA found that patients assigned to drink at least one cup of caffeinated coffee daily experienced fewer recurring episodes of atrial fibrillation or atrial flutter following electrical cardioversion than patients assigned to avoid caffeinated beverages. The six-month DECAF trial followed 200 adults and found arrhythmia recurrence in 47% of coffee drinkers compared with 64% of participants assigned to abstinence, corresponding to a 39% lower recurrence hazard in the time-to-event analysis. The findings challenge routine recommendations to avoid coffee among patients with existing atrial fibrillation, although the trial did not establish whether caffeine, coffee polyphenols, or associated behaviors produced the benefit. Host Dave Asprey explores caffeine's effects on cardiovascular function, adenosine signaling, and inflammation, explaining why individualized responses matter more than blanket dietary restrictions.
Sources:
https://doi.org/10.1001/jama.2025.21056

This episode is designed for biohackers, longevity enthusiasts, and high-performance listeners interested in Alzheimer's prevention, brain detoxification, immune aging, environmental toxins, peptide therapies, and cardiovascular optimization. Host Dave Asprey examines emerging research on glymphatic clearance, taurine and the NLRP3 inflammasome, PFAS removal through plasma donation, changing federal peptide regulations, and coffee's surprising relationship with atrial fibrillation, translating complex science into practical considerations for protecting cognitive function, reducing inflammation, and improving long-term health.

New episodes every Tuesday, Thursday, Friday, and Sunday.

Keywords: vibrating mattress brain detox, glymphatic system Alzheimer's, amyloid beta clearance, nitric oxide brain health, Piezo1 mechanosensitive channels, taurine inflammaging, NLRP3 inflammasome, taurine immune cells, Yale taurine study, chronic inflammation aging, PFAS forever chemicals, plasma donation PFAS removal, blood donation detox, PFOS reduction, BPC-157 peptide regulations, HHS peptide policy 2026, MOTS-c, Epitalon, KPV peptide, Semax, TB-500, FDA peptide compounding, coffee atrial fibrillation, DECAF clinical trial, caffeine heart health, cardiovascular longevity, Dave Asprey, The Human Upgrade, biohacking news 2026

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Timestamps:
00:00 - Intro
00:18 - Vibrating Mattress & Brain Clearance
01:54 - Taurine & Inflammation
03:17 - PFAS & Plasma Donation
05:26 - HHS Peptide Policy
07:32 - Coffee & Atrial Fibrillation
09:10 - Outro
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Get Roman Tsunder's book and learn more at https://pttow.com/

How to Master Any Skill, the Science of Peak Performance, Obsession, Deep Focus, Finding Your Purpose, Overcoming Failure, and Achieving Success Without Burnou

Host Dave Asprey sits down with Roman Tsunder, entrepreneur, founder of PTTOW!, and author of Plan to Take On the World, to explore the three ingredients of mastery, peak performance, obsession, deep focus, flow states, overcoming fear, and achieving success without sacrificing your health. Drawing on decades of experience bringing together influential entrepreneurs, creative leaders, and world-class performers, Roman reveals what separates people who become exceptional at their craft from those who struggle to reach their potential.

Roman introduces his OHF framework: Obsession, Hours, and Focus, explaining why these three ingredients consistently appear among people who achieve extraordinary results. Through examples including legendary surfer Kelly Slater, music producer Steve Aoki, and other high performers, he examines the difference between healthy obsession and compulsive ambition, why sustained practice matters, and what he calls "blackout focus." Dave challenges whether relentless dedication is always necessary and explores how some exceptionally successful people achieve mastery through curiosity, enjoyment, and flow rather than constant struggle.

The discussion turns to finding your purpose and developing a genuine passion for what you do. Roman explains why purpose may be easier to recognize through feelings of energy, excitement, and expansion than through intellectual analysis alone. He introduces practical approaches for identifying meaningful work, including revisiting childhood interests, recognizing recurring patterns of curiosity, and exploring what he calls a "shadow career." Dave and Roman discuss how reducing energy-draining responsibilities and spending more time on activities that naturally engage your attention can support both performance and fulfillment.

Finally, they examine failure, rejection, resilience, and the psychology of achievement. Roman recounts receiving 73 rejection letters from 72 Wall Street firms before pursuing a different entrepreneurial path. He explains how rejection can create unexpected opportunities and why the ability to recover from setbacks is essential to long-term success. Dave explores the connection between childhood adversity and ambition, the role of vulnerability in leadership, and how to distinguish productive challenges from destructive patterns of overwork.

You'll Learn:
How Roman's Obsession, Hours, and Focus framework explains the habits behind exceptional performance and mastery
Why healthy obsession differs from compulsive grinding, and how to pursue ambitious goals without sacrificing your health
How deep focus, sustained practice, and flow states contribute to developing expertise in almost any field
Why chronic stress and fight-or-flight activation can undermine performance, recovery, and long-term well-being
How breathwork, meditation, and nervous system regulation may help manage fear and improve performance under pressure
How to identify your purpose through personal interests, energizing activities, childhood experiences, and unexplored career ambitions
Why failure, rejection, vulnerability, and resilience play important roles in personal growth, leadership, and long-term achievement

Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living.

New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient.

Keywords: Roman Tsunder, Dave Asprey, PTTOW, Plan to Take On the World, mastery, skill mastery, peak performance, obsession, healthy obsession, deep focus, blackout focus, deliberate practice, high achievement, success habits, flow state, finding purpose, personal growth, motivation, discipline, burnout, chronic stress, fight or flight, nervous system regulation, breathwork, meditation, Transcendental Meditation, Joe Dispenza, fear, resilience, overcoming failure, rejection, childhood trauma, leadership, entrepreneurship, productivity, mental performance, biohacking, longevity

Resources:
• Get Roman Tsunder's book and learn more at https://pttow.com/
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• Danger Coffee: https://dangercoffee.com/discount/davetube
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Thank you to our sponsors!
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- Fatty15 | Go to fatty15.com/DAVE to get an additional 15% off their 90-day Starter Kit.

Timestamps:
00:00 - Trailer
01:02 - Intro
03:00 - The OHF Framework
10:07 - Talent, Genetics & Luck
15:30 - Grinding vs. Flow
20:00 - Fear as Fuel
24:57 - Breathwork & Healing
30:00 - Health & Corporate Awakening
36:00 - Lies Successful People Tell
43:00 - Finding Your Purpose
52:40 - Failure & Rejection
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Multivitamin Mistakes, MTHFR Genetics, B Vitamins, Creatine & Prescription Drug Risks

Host Dave Asprey sits down with Phil Cowley, a pharmacist, founder of Cache Valley Pharmacy, and creator of Phil's My Pharmacist, to explore multivitamins, prescription medications, supplement effectiveness, MTHFR genetics, methylated B vitamins, creatine, and the hidden problems within modern healthcare.

After opening his pharmacy in Logan, Utah, in 2001, Phil spent two decades serving patients and dispensing millions of prescriptions. By 2021, declining insurance reimbursements threatened his business despite increasing prescription volume. He turned to social media to share practical, affordable health advice, eventually building an audience of more than six million followers. Now, he explains what his experience behind the pharmacy counter taught him about medication side effects, nutritional deficiencies, supplement quality, and why conventional healthcare often overlooks individual biology.

The conversation examines common multivitamin mistakes, including the use of synthetic folic acid and pyridoxine (vitamin B6). Phil explains why certain nutrient forms may be less suitable for some individuals, how excessive B6 intake can cause peripheral neuropathy, and why buying more supplements doesn't necessarily improve health. They explore MTHFR genetic variants, methylation, and folate metabolism, including potential implications for cognitive function, inflammation, blood pressure, fertility, and neurological development.

Phil also reveals why creatine is his favorite supplement, discussing its potential benefits for brain health and muscle performance. He and Dave examine creatine dosing, hydration, electrolytes, absorption, and why creatine supplementation can influence kidney-related blood test results.

The discussion turns to Big Pharma, prescription drug pricing, and pharmacy benefit managers (PBMs). Phil shares how insurance reimbursement practices threatened his independent pharmacy despite increasing prescription volume. They also explore compounding pharmacies, customized hormone formulations, injectable vitamins, GLP-1 medications, and the challenges of providing personalized treatment within the conventional healthcare system.

Finally, Dave and Phil examine personalized medicine, genetic testing, medication interactions, and nutritional deficiencies, including the relationship between statins and CoQ10. They discuss why individual biology should guide supplement choices and how addressing underlying metabolic processes may offer a more comprehensive approach to long-term health.

This episode is essential listening for anyone interested in multivitamins, methylated B vitamins, MTHFR genetics, creatine, prescription drugs, supplement effectiveness, personalized nutrition, metabolic health, and longevity.

You'll Learn:
Why common multivitamins contain different forms of B vitamins, and how folic acid, folinic acid, L-methylfolate, and P5P differ
How MTHFR genetic variants influence folate metabolism and why individual responses to supplements can vary
What Phil recommends considering when using creatine for brain health, muscle performance, hydration, and kidney-related blood testing
How pharmacy benefit managers, insurance reimbursement, and drug pricing affect independent pharmacies and patient care
Why compounding pharmacies create customized medications, including hormone formulations, injectable vitamins, and certain GLP-1 treatments
How personalized supplementation, nutrient testing, medication interactions, and genetics may help inform more individualized healthcare decisions

Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living.

New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient.

Keywords: Phil Cowley, Phil's My Pharmacist, Dave Asprey, multivitamins, supplement mistakes, synthetic vitamins, methylated B vitamins, folic acid, methylfolate, MTHFR, methylation, vitamin B6, P5P, vitamin B12, folate metabolism, creatine, creatine dosage, brain health, kidney function, prescription drugs, drug interactions, pharmacy benefit managers, PBMs, Big Pharma, compounding pharmacy, GLP-1 medications, statins, CoQ10, personalized supplements, pharmacogenetics, longevity

Resources:
• Triquetra | Use code Dave20 at Triquetrahealth.com/dave for a discount
• Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/
• Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today.
• Danger Coffee: https://dangercoffee.com/discount/davetube
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Thank you to our sponsors!
- Butcher Box | Go to ButcherBox.com/HUMANUPGRADE to get $20 off your first box, plus your choice of free ground beef for life, or free chicken thigh
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Timestamps:
00:00 - Trailer
00:40 - Intro
01:45 - Drugs Stolen From Nature
06:05 - Listening to Patients
09:33 - Pharmacy Business & PBMs
14:10 - Compounding Pharmacy Explained
20:42 - Why Creatine Is Amazing
28:23 - MTHFR & Methylation
46:44 - Lab Tracking & Longevity
50:58 - Science Bullies & Urine Therapy
59:19 - Future of Pharmacy
01:03:01 - TriQuetra Health & Closing
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I've tried every controversial focus drug I could get my hands on. Modafinil, LSD, psilocybin, mescaline, DMT, ketamine, MDMA, amphetamine, ephedrine, the racetams, and a shelf of Russian compounds most people have never heard of. I've spent 20 years and millions of dollars testing this on my own brain, and here's what I found: some of them work, most don't do what you've been told, and none of them are free.

But the one I'd crown above all of them is legal, costs almost nothing, and you can buy it this afternoon. You've just been lied to about it for 60 years by the people who made a fortune doing it. In this video I'll show you what each compound actually does inside your brain, what it takes from you on the other side, and the four rules I follow so the best one doesn't turn into the worst one.

You'll Learn:
Why modafinil is considered the closest thing to a "Limitless pill" and how it affects sleep
How LSD, psilocybin, MDMA, and ketamine affect the brain differently from focus drugs
Why Adderall and amphetamines can make you hyper-focused on the wrong things
How racetams became the original nootropics for cognitive enhancement
What Russian scientists developed for cosmonauts and soldiers, including bromantane, Semax, and Selank
Why pharmaceutical nicotine ranks among the most controversial focus enhancers
How nicotine affects acetylcholine, attention, memory, and potentially brain aging
Why nicotine and smoking have very different health risks
How delivery speed influences addiction risk, from cigarettes to patches and lozenges
Dave's four rules for reducing nicotine risks and who should avoid it
What Dave learned from spending $2.5 million experimenting with cognitive enhancement

Timestamps:
00:00 - Trailer
01:07 - Modafinil: The Limitless Pill
03:45 - Psychedelics vs. Focus Drugs
05:31 - Microdosing & The Placebo Effect
07:43 - Cocaine & Drug Tolerance
08:33 - Amphetamines & Adderall
17:09 - Racetams: The Original Nootropics
21:12 - Russian Smart Drugs
29:17 - Nicotine for Focus & Cognition
33:53 - Nicotine Risks & Safety Rules

Thank you to our sponsors!
-Kenetik | Instead of pushing your system harder, Kenetik feeds your brain the ketones it craves to fuel calm clarity and steady focus. Go to drinkkenetik.com/DAVE and use code DAVE for a discount.
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-Simplify | This episode is sponsored by Simplify. You’ve built your nest egg. Now see how XV can help you put it to work. Visit Simplify.us/NestEgg to learn more.
-Butcher Box | Go to ButcherBox.com/HUMANUPGRADE to get $20 off your first box, plus your choice of free ground beef for life, or free chicken thigh

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Placebos Improved IBS Symptoms Even When Patients Knew the Pills Were Inactive
In a randomized trial of 80 adults with irritable bowel syndrome, participants who knowingly took placebo pills reported greater symptom improvement than those receiving no treatment. After three weeks, 59% of the placebo group reported adequate relief compared with 35% of controls. A larger follow-up study also found that openly prescribed placebos improved reported IBS symptoms more than a no-pill control. Host Dave Asprey explores how conditioning, expectations, and the ritual of taking a treatment may influence symptoms without deception. He explains why these findings do not mean symptoms are imaginary or that positive thinking can cure disease, but raise questions about how the brain, treatment context, and learned physiological responses shape the experience of illness.
Sources:
PLOS ONE: Placebos Without Deception—A Randomized Controlled Trial in Irritable Bowel Syndrome
Pain: Open-Label Placebo vs. Double-Blind Placebo for Irritable Bowel Syndrome
Harvard Health: A Placebo Can Work Even When You Know It’s a Placebo

Once-Weekly Wall Squats Preserved Some Blood-Pressure Benefits After More Frequent Training
A randomized trial involving 100 adults found that isometric wall-squat training reduced blood pressure, with some benefits maintained after participants cut back to one or two sessions per week. The important detail is that participants first completed four weeks of training three times weekly. Those who subsequently reduced to one weekly session finished the eight-week study with systolic blood pressure approximately 6.6 mmHg below baseline, while those continuing three weekly sessions experienced the largest improvement. Host Dave Asprey explores how sustained muscle contractions may influence vascular resistance and autonomic regulation, and why the minimum dose needed to maintain a benefit can differ from the dose needed to build it. He explains why this study does not show that beginners get the same results from one weekly session or that wall squats replace medication.
Sources:
BMJ Open Sport & Exercise Medicine: Isometric Exercise Training and Blood Pressure Control
Full Study: Exploring the Dose-Response to Training Frequency

Expert Birdwatchers Showed Brain Differences Linked to Attention and Perception
A study comparing 29 expert birdwatchers with 29 beginners found differences in brain structure and activity associated with bird-identification expertise. Experts showed lower mean diffusivity in regions involved in attention and perception, an MRI finding researchers interpreted as more compact tissue organization. Some differences were also present in older experts, raising questions about how sustained learning may relate to cognitive aging. Host Dave Asprey examines why birdwatching involves more than spending time outdoors: identifying unfamiliar species requires attention, visual discrimination, memory, and continued learning. He explains why these findings are interesting without proving that birdwatching prevents dementia or slows cognitive decline, since researchers cannot determine whether the hobby caused the differences or whether preexisting characteristics helped people become experts.
Sources:
The Journal of Neuroscience: The Tuned Cortex—Expertise-Related Structural and Functional Remodeling Across the Adult Lifespan
Society for Neuroscience: Skills From Being a Birder May Change—and Benefit—Your Brain
BBC Future: Birdwatching Rewires the Brain and Slows Cognitive Decline

Early THC Exposure Changed Serotonin Signaling in Mice Through an mTOR-Related Pathway
A mouse study found that chronic THC exposure beginning early in life altered signaling through serotonin 5-HT2A receptors and increased sensitivity to a subsequently administered serotonergic drug. THC alone did not significantly disrupt the study’s baseline sensorimotor-gating measure, but previously exposed mice showed a greater disruption after the additional drug challenge. Giving rapamycin during THC exposure prevented several signaling changes and the heightened behavioral response, implicating the Akt/mTOR pathway. Host Dave Asprey explores how cannabinoid exposure may influence other neurotransmitter systems and why the timing of exposure matters when interpreting the experiment. He emphasizes that this was a mechanistic animal study, not proof that all cannabis use causes psychosis or that rapamycin can prevent cannabis-related psychiatric effects in humans.
Sources:
PubMed: Chronic Cannabis Promotes Pro-Hallucinogenic Signaling of 5-HT2A Receptors Through the Akt/mTOR Pathway
Neuropsychopharmacology: Full Study

Pornography Consumption Was Linked to Brain Differences, but Cause and Effect Remain Unclear
A brain-imaging study of 64 healthy men found that greater reported pornography consumption was associated with lower gray-matter volume in part of the right caudate, lower activation in the left putamen during a sexual-image task, and lower functional connectivity between the right caudate and a prefrontal region involved in cognitive control. Host Dave Asprey examines what these findings may suggest about reward processing, repeated exposure, and habituation while distinguishing those possibilities from claims the study did not establish. Researchers did not directly measure dopamine depletion, demonstrate brain damage, or show that pornography caused the observed differences. Because participants were assessed at one point in time, preexisting brain characteristics could also help explain differences in consumption. The study raises questions about behavior and brain biology without resolving which came first.
Sources:
JAMA Psychiatry: Brain Structure and Functional Connectivity Associated With Pornography Consumption—The Brain on Porn
National Center on Sexual Exploitation: Research Spotlight—The Brain on Porn

This episode is designed for biohackers, longevity enthusiasts, people interested in cognitive performance and cardiovascular health, and anyone trying to separate provocative brain research from proven cause and effect. Host Dave Asprey examines why placebos may improve symptoms without deception, how reduced-frequency wall-squat training can preserve some blood-pressure benefits, what expert birdwatchers reveal about learning and the aging brain, how early THC exposure altered serotonin signaling in mice, and what pornography brain-imaging research can actually establish. The larger lesson is evidence: distinguish symptom relief from disease treatment, maintenance from improvement, brain differences from brain damage, and a compelling animal mechanism from a proven human intervention.

Keywords: open label placebo, placebo without deception, placebo effect, placebo IBS study, irritable bowel syndrome, mind body connection, conditioning and symptoms, wall squats blood pressure, wall sit exercise, isometric exercise training, minimum effective exercise dose, systolic blood pressure, vascular resistance, autonomic regulation, birdwatching brain health, birding cognitive aging, cognitive longevity, neuroplasticity, attention and memory, skill learning brain, THC brain research, cannabis serotonin signaling, cannabis psychosis research, 5-HT2A receptors, Akt mTOR pathway, rapamycin research, pornography brain study, pornography reward circuitry, caudate nucleus, brain imaging research, correlation versus causation, Dave Asprey, The Human Upgrade, biohacking research roundup

Thank you to our sponsors!
Simplify | This episode is sponsored by Simplify. You’ve built your nest egg. Now see how XV can help you put it to work. Visit Simplify.us/NestEgg to learn more.
Neuronic | Go to www.neuronic.online Code DAVE for $100 off
Puori | Use my code DAVE at P-U-O-R-I dot com slash D-A-V-E for 32% off Puori Fish Oil when you start a subscription. That’s puori.com slash DAVE, and use code DAVE at checkout.
iRestore | Unlock your best hair & skin with @iRestorelaser and HUGE savings on iRESTORE with code DAVE at irestore.com/DAVE

Resources:
• Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/
• Get My 2026 Biohacking Trends Report: https://daveasprey.com/2026-biohacking-trends-report/
• Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today.
• Danger Coffee: https://dangercoffee.com/discount/dave15
• My Daily Supplements: SuppGrade Labs (15% Off)
• Favorite Blue Light Blocking Glasses: TrueDark (15% Off)
• Dave Asprey’s BEYOND Conference: https://beyondconference.com
• Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated
• Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/
• Upgrade Labs: https://upgradelabs.com
See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.